Sharper Focus
Focus in 30 minutes. Lasting up to 5 hours. Clarity without caffeine.
Stronger Memory
Supports recall, retention and cognitive processing speed.
Long-Term Brain Health
Supports neuroplasticity and healthy brain cells.
Vitamins & Minerals
Vegan
Gluten Free
Non-GMO
Proven Benefits - Backed by Science
Five ingredients. Every one earning its place. SIGNAL is built around a short, precise stack of branded and clinically studied actives. No filler ingredients. No proprietary blends hiding doses. Every compound is present at a meaningful level, chosen because the evidence supports it.
Powered by Zynamite®
Most cognitive supplements work slowly — if at all. Zynamite® is different. This patented mango leaf extract, standardised to 60%+ mangiferin, has been shown in double-blind, placebo-controlled human trials to activate within 30 minutes, improving attention, processing speed, and episodic memory for up to 5 hours. It works via a distinct neurological pathway — without relying on stimulants or borrowing against your nervous system.
Driven by Cognizin® Citicoline
Your brain consumes around 20% of your body’s total energy. Cognizin® supports this demand at the source — increasing phosphatidylcholine levels to maintain healthy cell membranes and optimise neurotransmitter production. Multiple peer-reviewed studies in healthy adults show improvements in memory, focus, and mental energy at clinically relevant doses.
With TheaGreen® L-Theanine
Focus isn’t forced — it’s created. TheaGreen® promotes alpha brainwave activity — the same state associated with calm, present attention. EEG-based research shows increased alpha wave production following L-theanine intake, supporting a more stable, sustained form of focus. With only 0.83mg naturally occurring caffeine per serving, there’s no spike, no crash — just clarity.
Supported by Lion’s Mane Mushroom
Most ingredients maintain. Lion’s Mane goes further. Its bioactive compounds stimulate Nerve Growth Factor (NGF), essential for neuron growth, repair, and connectivity. Human studies in older adults show improvements in cognitive function with consistent use, with benefits building progressively over time.
From Korean Ginseng (Panax ginseng)
Cognitive performance is as much about resilience as it is about output. Korean Ginseng works as an adaptogen, helping regulate the body’s stress response via the HPA axis. Clinical trials have shown improvements in mental performance and reduced fatigue under stress, supporting a more stable, resilient cognitive state.
B-Vitamins & Zinc
Cognitive performance depends on the underlying system. SIGNAL includes a full spectrum of B-vitamins — including methylated B12, folate, and B6 — to support neurotransmitter production, energy metabolism, and homocysteine regulation. Zinc contributes to normal cognitive function. These nutrients carry established, EFSA-approved claims — forming the essential foundation that allows everything else to work effectively.
Your Journey with Signal
What to expect over time
Follow the timeline below to see the progressive benefits and improvements you can expect with consistent use.
First Signal
- Zynamite® activates - sharper attention and faster processing
- Mental clarity lifts noticeably
- Focus comes more easily, without any stimulant effect
- Calm, alert energy - no jitters, no edge
Your Cognitive Peak
- Sustained focus window - the ingredients are actively working
- Easier to stay on task through demanding work
- Reduced mental fatigue in the afternoon
- Composed, clear thinking under pressure
Noticeable Gains
- Fewer afternoon brain fog episodes
- Easier to get into flow and stay there
- Calmer, more composed mental state through the day
- Sleep quality may begin to improve
Building Momentum
- Cognizin® building - sharper memory and recall
- More consistent concentration across the full day
- Mental resilience under sustained pressure improving
- Cognitive energy feels more reliable
Noticeable Results
- Meaningful improvement in cognitive stamina and clarity under pressure
- Brain fog feels like the exception, not the norm
- Memory and recall noticeably sharper
- Mental performance holds even on high-demand days
Long-Term Brain Health
- Lion’s Mane continuing to support Nerve Growth Factor production
- Neuroprotective benefits compounding over time
- Cognitive resilience and mental clarity maintained as you age
- Your sharpest, most consistent daily performance - as a baseline
Sharper focus without stimulants
Zynamite® activates within 30 minutes, delivering clinical-grade focus that holds for up to 5 hours — with no caffeine dependency.
Fewer brain fog moments
Cognizin® and the B-vitamin complex support neurotransmitter production and brain energy metabolism — the two leading drivers of mental fog.
Calm under pressure
Korean Ginseng acts as an adaptogen — reducing the mental impact of sustained stress without sedation or overstimulation.
Sustained concentration
L-Theanine promotes calm, alert focus — particularly effective during sustained cognitive demands like deep work or complex decisions.
Long-term brain health
Lion’s Mane stimulates the production of Nerve Growth Factor (NGF), supporting neuroplasticity and long-term cognitive resilience.
Sharper memory and recall
Cognizin® has been clinically shown to support memory function in healthy adults, with particular evidence in women in midlife.
| Supplement Information | Amount per 2 Capsules | Providing |
|---|---|---|
| Mango Leaf Extract 4:7:1 (Zynamite®) | 300mg | Min 270mg Mango Leaf Extract, Min 45mg Mangiferin |
| Citicoline (Cognizin®) | 250mg | Min 245mg Citicoline |
| Green Tea Extract (TheaGreen® L-Theanine) | 167mg | 100mg L-Theanine, Max 0.83mg Caffeine |
| Lion's Mane Mushroom Extract 12:1 | 125mg | 112.5mg Lion's Mane Extract |
| Korean Ginseng Extract 10:1 | 100mg | Min 20mg Total Ginsenosides |
| Vitamins & Minerals | Amount per 2 Capsules | % Reference Intake |
| Niacin | 4.8mg NE | 30% |
| Vitamin B6 | 0.42mg | 30% |
| Folic Acid | 60μg | 30% |
| Vitamin B12 | 12.5μg | 500% |
| Pantothenic Acid | 1.8mg | 30% |
| Zinc | 3mg | 30% |
Actually noticed a difference within a week
I've tried a few nootropics over the years and most felt like expensive placebos. SIGNAL is different — I noticed sharper focus in the afternoons within the first few days, which is exactly when I normally hit a wall. Six weeks in and the brain fog that used to derail my mornings is genuinely less frequent. I take it with my HIRO hydration every morning. Feels like a proper routine now.
Rachel M.
Verified Buyer
The clearest head I've had in years
I'm 47, work full time, and have two teenagers — my brain is pulled in twelve directions every day. I started SIGNAL hoping to get through afternoons without the usual fog and that is exactly what happened. No dramatic claims, just consistently clearer thinking. Two months in, and I'd genuinely notice if I forgot to take it.
Joanna T.
Verified Buyer
The formulation is well thought through — branded actives at meaningful doses, no redundant ingredients, and the inclusion of methylated B12 rather than the cheaper cyanocobalamin form is a detail that shows genuine care for bioavailability. The combination of Zynamite® for fast-acting focus and Cognizin® for longer-term cognitive support is a clinically sensible stack. This is one of the more credible nootropic formulas I have seen in the consumer supplement space.
Dr. Sarah Okafor
Functional Medicine Practitioner
HOW TO USE: SIGNAL
Clear thinking, every day — without the spikes or crashes
Take 2 capsules daily with water, ideally in the morning or early afternoon as part of your routine.
Consistency matters more than timing. You can take Signal any time of day, but most people prefer it in the morning for focus, or early afternoon to stay sharp without relying on caffeine.
Signal is designed for daily use, with both immediate effects and long-term cognitive support building over time.
Ingredients & Benefits
What's Inside?
60-DAY RISK-FREE PROMISE
Frequently Asked Questions
About HIRO
HIRO creates premium daily wellbeing products designed to simplify modern nutrition. Our formulations focus on carefully selected ingredients, meaningful dosages and thoughtful formulation.
What is HIRO?
HIRO is a wellness brand focused on creating high-quality daily nutrition products designed to support hydration, energy and overall wellbeing.
Our products simplify complex supplement routines by combining carefully selected ingredients into convenient daily formats.
What makes HIRO different from other supplement brands?
Many supplements focus on long ingredient lists but contain extremely small amounts of each ingredient.
HIRO focuses on carefully balanced formulations that prioritise potency, efficacy and bioavailability rather than simply maximising ingredient count.
Do HIRO products use clinically studied ingredient levels?
Where possible, HIRO formulations aim to reflect ingredient levels supported by scientific research.
This helps ensure ingredients are present at levels designed to deliver meaningful nutritional value.
What does bioavailability mean?
Bioavailability refers to how efficiently nutrients can be absorbed and used by the body.
The form of an ingredient, the surrounding nutrients and the formulation itself all influence bioavailability.
Why not simply include as many ingredients as possible?
More ingredients does not necessarily mean a better supplement.
Many products contain very long ingredient lists but include extremely small amounts of each ingredient.
HIRO focuses on thoughtful formulation and meaningful ingredient levels.
Can I take multiple HIRO products together?
Yes. HIRO products are designed to complement each other as part of a daily wellbeing routine.
How long before I feel the benefits?
Many people begin to notice benefits after 4–8 weeks of consistent use.
Where are HIRO products made?
HIRO products are developed in the United Kingdom and manufactured in European facilities that follow strict quality and food safety standards.
Are HIRO products safe for children?
HIRO products are not recommended for individuals under 18 years of age.
Can I take HIRO alongside medication?
If you are taking prescription medication or have a medical condition, consult your healthcare professional before introducing any new supplement.
SIGNAL Nootropic
SIGNAL is HIRO's advanced daily nootropic — a precise stack of clinically studied ingredients designed to support focus, mental clarity and long-term brain health. Two capsules a day, taken consistently, is all it takes.
What is SIGNAL?
SIGNAL is a daily nootropic capsule formulated to support cognitive performance. It combines five clinically studied active ingredients — Zynamite®, Cognizin®, TheaGreen® L-Theanine, Lion's Mane mushroom and Korean Ginseng — alongside a B-vitamin complex and zinc.
It is designed for anyone who needs sustained mental clarity, sharper focus and better cognitive resilience through demanding days.
What benefits does SIGNAL support?
SIGNAL is designed to support:
- sustained focus and concentration
- mental clarity and reduction of brain fog
- memory and recall
- calm, alert energy without overstimulation
- cognitive resilience under pressure
- long-term brain health
What are the key ingredients in SIGNAL?
SIGNAL is built around five clinically studied active ingredients:
- Zynamite® (mango leaf extract, 300mg) — supports fast-acting mental energy and focus
- Cognizin® (citicoline, 250mg) — supports memory, attention and brain health
- TheaGreen® (L-Theanine from green tea, 167mg) — promotes calm, alert focus
- Lion's Mane mushroom extract (125mg) — supports neurological health and cognitive resilience
- Korean Ginseng extract (100mg) — supports mental performance under stress
The formula is completed with Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid and Zinc — all contributing to normal cognitive and nervous system function.
What makes SIGNAL different from other nootropics?
Most nootropics on the market either rely on caffeine for a short-term lift, or use generic ingredients at doses too low to be clinically meaningful. SIGNAL uses only branded, patented actives — Zynamite® and Cognizin® specifically — at clinically relevant doses, with fully transparent labelling. No proprietary blends, no hidden doses.
Who is SIGNAL designed for?
SIGNAL is designed for anyone navigating a demanding daily life who wants their brain to work at its best consistently. It is particularly well suited to people experiencing brain fog, afternoon cognitive slumps, or difficulty sustaining focus through long days. It is suitable for vegans and vegetarians.
What is Zynamite®?
Zynamite® is a patented mango leaf extract (Mangifera indica) from Nektium, standardised to contain over 60% mangiferin — a naturally occurring polyphenol with well-documented effects on brain function.
Clinical research shows that a single dose produces measurable improvements in attention, processing speed, episodic memory and cognitive flexibility — with effects detectable within 30 minutes and lasting up to 5 hours. Unlike caffeine, Zynamite® works through a different mechanism in the brain, which means it delivers similar alertness and focus without jitteriness, elevated heart rate or the crash that follows a caffeine hit.
It is sustainably sourced as a by-product of mango cultivation.
What is Cognizin®?
Cognizin® is a patented, highly bioavailable form of citicoline from Kyowa Hakko, backed by over 16 years of clinical research. It is the only form of citicoline studied specifically in healthy adults — not just clinical populations.
Citicoline supports the production of phosphatidylcholine (essential for brain cell membrane health), acetylcholine (a key neurotransmitter for memory and learning) and brain energy metabolism. One study found a 13.6% increase in brain ATP in healthy adults after six weeks of daily use.
Notably, research has specifically demonstrated improvements in attention and cognitive performance in middle-aged women — making it particularly relevant for the life stage at which many HIRO customers are taking SIGNAL.
A separate 12-week clinical trial in adults aged 50 to 85 showed meaningful improvements in overall memory, particularly episodic memory. Cognizin® is vegetarian, allergen-free and non-stimulant.
What does Lion's Mane mushroom do?
Lion's Mane (Hericium erinaceus) is a medicinal mushroom with a growing body of research supporting its role in neurological health. It is associated with supporting neurogenesis — the brain's ability to maintain and develop nerve cells — as well as cognitive resilience over time.
Is SIGNAL a stimulant?
No. SIGNAL is not a stimulant. It does not rely on caffeine or stimulant compounds to produce its effects.
Zynamite® supports mental energy through a different mechanism to caffeine, and TheaGreen® L-Theanine actively promotes a calm, focused state. The result is clear-headed focus without jitteriness or a crash.
Does SIGNAL contain caffeine?
SIGNAL contains no added caffeine. The green tea extract (TheaGreen®) used in the formula contributes a negligible trace amount — well below any level associated with stimulant effects.
How do I take SIGNAL?
Take two capsules per day with water. Mid-morning works best for most people — after your natural cortisol peak, when your baseline alertness begins to taper and the ingredients can do the most work.
Each pack contains 56 capsules — a 28-day supply.
When is the best time to take SIGNAL?
We recommend around 11am — after your body's natural morning cortisol peak has begun to taper. This is when many people first feel their focus starting to dip, and the point at which SIGNAL's ingredients can make the most meaningful difference to clarity and concentration through the rest of your day.
How long before I notice results?
Some ingredients in SIGNAL — particularly Zynamite® and L-Theanine — can support focus and mental clarity relatively quickly. Others, such as Cognizin® and Lion's Mane, build their effects progressively with consistent daily use.
Most customers notice meaningful improvements in clarity and cognitive stamina within 2 to 4 weeks. Long-term benefits to brain health and resilience develop over months of consistent use.
Is SIGNAL suitable for daily long-term use?
Yes. SIGNAL is designed as a daily supplement intended for consistent, long-term use. The ingredients are selected to support cumulative cognitive health rather than short-term stimulation.
Is SIGNAL vegan?
Yes. SIGNAL capsules use hydroxypropyl methylcellulose (HPMC) — a plant-derived capsule shell. The formula contains no animal-derived ingredients and is suitable for vegans and vegetarians.
Does SIGNAL contain any allergens?
SIGNAL does not contain any of the 14 major allergens. It is free from gluten, dairy, soy, nuts and artificial additives.
Can I take SIGNAL with other HIRO products?
Yes. SIGNAL is designed to complement other HIRO products as part of a daily wellbeing stack. It works particularly well alongside HIRO Hydration tablets to support both mental and physical performance through the day.
Can SIGNAL help with brain fog?
Brain fog — that feeling of mental cloudiness, slow thinking or difficulty concentrating — is one of the most common reasons people try SIGNAL.
The formula addresses several of the underlying mechanisms associated with cognitive fatigue. Cognizin® supports neurotransmitter production tied to mental clarity. Zynamite® supports alertness without stimulants. Lion's Mane contributes to longer-term neurological resilience. And the B-vitamin complex, particularly B12 and B6, supports normal nervous system function.
Many of our customers are women in their 40s and 50s who notice brain fog worsening through perimenopause. While SIGNAL is not a medical treatment, consistent daily use alongside good sleep and nutrition can meaningfully support mental clarity during this life stage.
Can I take SIGNAL if I am pregnant or breastfeeding?
If you are pregnant or breastfeeding, we recommend speaking with your healthcare professional before introducing any new supplement.
Can I take SIGNAL alongside medication?
If you are taking prescription medication or have a medical condition, consult your healthcare professional before use.
Wellness & Supplement Questions
What are nootropics?
Nootropics are ingredients — plant extracts, nutrients or compounds — that support cognitive function, including focus, memory, mental clarity and brain health.
The term covers a wide spectrum, from well-studied branded ingredients like Cognizin® and Zynamite® through to herbs such as Lion's Mane and Ginseng that have been used for centuries in traditional medicine.
Quality nootropic supplements use ingredients at clinically studied dosages, are transparent about what they contain, and are free from proprietary blends that obscure how much of each ingredient you are actually getting.
What are electrolytes?
Electrolytes are minerals such as sodium, potassium and magnesium that help regulate hydration, muscle function and nerve signalling.
Do electrolyte tablets help hydration?
Electrolytes help regulate how fluids move through the body and support hydration.
What are superfood powders?
Superfood powders are concentrated blends of plant-based ingredients designed to support daily nutrition.
Do greens powders actually work?
The effectiveness of a greens powder depends on formulation quality, ingredient levels and bioavailability.
How should I choose a high quality supplement?
- ingredient quality
- clinically studied dosages
- bioavailability
- transparent formulation
General
Are any HIRO products safe for children?
We do not recommend HIRO to anyone under 18.
Can HIRO products help with weight loss?
Taking any supplement when on a restricted diet can help to give your body the nutrients it needs to keep on trucking. So if you are restricting your diet to lose weight or for any other reason, HIRO can help give your mind, body and guts what they're missing.
How long before I start to feel the effects of using HIRO products?
We are all different but if you take HIRO regularly you will start to feel the benefits after 1–2 months.
Do I need to take a break from HIRO products?
No, we don't believe you do.
Can I drink alcohol when taking HIRO products regularly?
HIRO is made for real people like us. We drink. We go out. We sometimes eat junk food. We take HIRO to offset.
Do HIRO products have to be used within a narrow time frame?
Our HIRO Superfood blends have a shelf life of 12 months.
Subscriptions
How does the subscription service work?
Select 'Subscribe & Save', add your product to your basket and checkout as normal. We'll then send you the same product every month. You can pause, cancel and update at any time.
Can I cancel anytime?
Yes you can. Just head over to your account page and manage your subscription from there.
Can I change how often I receive my products?
Absolutely. Head over to your account page and manage your subscription from there. You can change frequency to weeks or months.
Can I skip or pause my subscription?
Yes you can. Skip, pause or cancel at any time. Head over to your My Account page and log in. Once logged in, click on Manage Subscriptions. Here you can make any changes you like.
Delivery & Returns
Who do you use for delivery?
We use Royal Mail.
What's the difference between Standard and Express delivery?
- Standard delivery uses Royal Mail's 48hr tracked service. This means you'll get your order in 2–3 working days.
- Express delivery uses Royal Mail's 24hr tracked service. This means you'll get your order in 1–2 working days.
What if I don't like what I've received?
If you're not 100% satisfied with HIRO, please get in touch with us at [email protected] and we'll do everything we can to fix things for you.
Is your packaging recyclable?
Yes, our boxes are 100% recyclable and are made from recycled and sustainable materials.
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